Ventricular Tachycardia Revealing an Anderson– Fabry Disease: A Rare Case Report

Anderson-Fabry disease ranks as the second most common lysosomal storage disorder. It is a hereditary and rare metabolic condition resulting from a mutation in the GLA gene, responsible for encoding the lysosomal enzyme alpha-galactosidase A. This condition impacts multiple organs in the body, leading to symptoms like cerebrovascular and cardiac problems, chronic renal failure, skin lesions, peripheral neuropathy, and various other abnormalities. While the cardiac manifestations of Fabry disease are well-documented in the medical literature, occurrences where cardiac symptoms are the initial and sole clinical sign of Fabry disease are relatively infrequent. This case report highlights one such unusual situation in which persistent ventricular tachycardia serves as the first and exclusive indication of cardiac involvement in Fabry disease.