Inflammatory Response Post PCI Technique

Each year, millions of patients with coronary heart disease worldwide are treated by means of percutaneous coronary intervention which induces a significant inflammatory reaction in the injured vessel wall that leads to the development of neointimal thickening and restenosis. The systemic inflammatory response after technique that can be measured in the plasma by the inflammatory markers and can be detected by the concentration of these markers after the procedure and its related to a greater risk of adverse clinical outcomes. There was a strong correlation between the extent of inflammatory reaction and the amount of neointimal formation within the stents and both inflammatory changes and the arterial injury can cause a neointimal reaction independently, even in the absence of the other.