In silico ANALYSIS OF PHYTOCHEMICALS FROM Coriandrum sativum AGAINST Cyclopropane-Fatty-Acyl-Phospholipid SYNTHASE OF Lactobacillus casei

RANA, GEETANJALI and PANDA, SWATIPRAVA and MOHAPATRA, ABINASH and PANDEY, MUKUNDJEE and BHATTACHARYAY, DIPANKAR (2020) In silico ANALYSIS OF PHYTOCHEMICALS FROM Coriandrum sativum AGAINST Cyclopropane-Fatty-Acyl-Phospholipid SYNTHASE OF Lactobacillus casei. PLANT CELL BIOTECHNOLOGY AND MOLECULAR BIOLOGY, 21 (9-10). pp. 6-11.

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Abstract

Phytochemicals are non-nutritive compounds obtained from plants. It has been reported that Coriandrum sativum plant extract is used to cure tooth cavity. The plant extract contains different phytochemicals. Tooth cavity is caused by Lactobacillus casei. One of the key enzymes involved in its biochemical pathway is cyclopropane-fatty-acyl-phospholipid synthase. The molecular docking of the phytochemicals with the enzyme was studied using Biovia Discovery Studio. The strength of the interaction was evaluated based on -CDocker energy and -CDocker interaction energy. High positive values for both the parameters indicated that out of different phytochemicals petroselinic acid can effectively deactivate the cyclopropane-fatty-acyl-phospholipid synthase enzyme thereby interrupting the life cycle of Lactobacillus.

Item Type: Article
Subjects: Eprints STM archive > Biological Science
Depositing User: Unnamed user with email admin@eprints.stmarchive
Date Deposited: 04 Dec 2023 03:59
Last Modified: 04 Dec 2023 03:59
URI: http://public.paper4promo.com/id/eprint/1587

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