Huang, Liqin and Zhang, Zhaohui (2022) CSPα in neurodegenerative diseases. Frontiers in Aging Neuroscience, 14. ISSN 1663-4365
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Abstract
Adult-onset neuronal ceroid lipofuscinosis (ANCL) is a rare neurodegenerative disease characterized by epilepsy, cognitive degeneration, and motor disorders caused by mutations in the DNAJC5 gene. In addition to being associated with ANCL disease, the cysteine string proteins α (CSPα) encoded by the DNAJC5 gene have been implicated in several neurodegenerative diseases such as Alzheimer's disease (AD), Parkinson's disease (PD), and Huntington's disease. However, the pathogenic mechanism responsible for these neurodegenerative diseases has not yet been elucidated. Therefore, this study examines the functional properties of the CSPα protein and the related mechanisms of neurodegenerative diseases.
| Item Type: | Article |
|---|---|
| Subjects: | Eprints STM archive > Medical Science |
| Depositing User: | Unnamed user with email admin@eprints.stmarchive |
| Date Deposited: | 28 Apr 2023 07:34 |
| Last Modified: | 20 Sep 2023 07:53 |
| URI: | http://public.paper4promo.com/id/eprint/92 |
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